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>Home >Faculty >Cheng-Ruei Lee, Assistant Professor
Cheng-Ruei Lee, Assistant Professor
 
Title Assistant Professor
Education Duke University, USA
Postdoc: Gregor Mendel Institute of Molecular Plant Biology, Austria
Specialty Evolutionary genetics
Evolutionary genomics
Quantitative genetics
Genetic mapping
E-mail chengrueilee@ntu.edu.tw
Lab Life Science Building R1129
Lab Web

https://sites.google.com/site/chengrueilee/

Tel 02-3366-2535
Fax  
Research Interests
1. The genetic and genomic changes underlying weedy plant evolution.
2. The evolution of wild relatives of important economical species.
Lab Introduction

Our lab is interested in any topic broadly related with evolutionary and ecological genetics and genomics, specifically, how do genes, genomes, environments, complex traits, and natural selection interact with and shape the patterns of each other? What is your favorite species? Let's explore the interesting story behind it!

        We use a highly integrative and interdisciplinary approach for our research, incorporating knowledge and techniques in field ecology, population genetics, quantitative genetics, molecular biology, genomics, and bioinformatics. Perspective students are expected to be enthusiastic about evolution. Having prior knowledge of any of these fields is great, but not necessary.      

We are interested in (but not limited to) these important questions:

Does local adaptation facilitate speciation?

Why is there genetic variation, and what maintains it?

What are the factors shaping geographical patterns of genomic variation?

Some genomic regions are more polymorphic than others. Why?

What are the genomic regions or genes controlling adaptive traits?

Are they few genes each with large effect, or many genes each with small effect?

Does the adaptive allele come from novel mutation or standing genetic variation?

In addition, we are also interested in the evolution and relationship of human-associated plants with their wild relatives, including the weed Arabidopsis thaliana and economically important species such as rice and soybean. Our group highly welcome those who are interested in ecological and evolutionary genetics and genomics!

Publications: (See the full list of publications in my website)

The 1001 Genomes Consortium. 2016. 1135 genomes reveal the global pattern of polymorphism in Arabidopsis thaliana. Cell 166:481-491 

Lee, C-R, JT Anderson, and T Mitchell-Olds. 2014. Unifying genetic canalization, genetic constraint, and genotype-by-environment interaction: QTL by genomic background by environment interaction of flowering time in Boechera stricta. PLoS Genetics 10(10):e1004727 

Lee, C-R and T Mitchell-Olds. 2013. Complex trait divergence contributes to environmental niche differentiation in ecological speciation of Boechera stricta. Molecular Ecology 22(8):2204-2217 

Lee, C-R and T Mitchell-Olds. 2012. Environmental adaptation contributes to gene polymorphism across the Arabidopsis thaliana genome. Molecular Biology and Evolution 29(12):3721-3728 

Prasad, K, B-H Song, C Olson-Manning, JT Anderson, C-R Lee, ME Schranz, AJ Windsor, MJ Clauss, AJ Manzaneda, I Naqvi, M Reichelt, J Gershenzon, SG Rupasinghe, MA Schuler, and T Mitchell-Olds. 2012. A gain-of-function polymorphism controlling complex traits and fitness in nature. Science 337:1081-1084

Lee, C-R and T Mitchell-Olds. 2011. Quantifying effects of environmental and geographical factors on patterns of genetic differentiation. Molecular Ecology 20(22):4631- 4642

Courses offered
  • EEB7002

    Research Training

    EEB5045

    Population Genetics

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